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Microbiology Pioneers:

       Robert Koch (1843-1910)

 Contributions:

       In 1872, Koch began epoch-making researches which allowed advancement in his rank amongst other workers in science ("Robert Koch..."). In 1882, he scientifically proved why the anthrax bacilli of the epidemic disease at the time, anthrax, was what caused anthrax ("Robert Koch..."). The method he developed, now known as Koch’s postulates is the basic procedure used today to prove a disease’s etiology ("Robert Koch..."). His procedure also introduced how to culture pure bacteria. Through this experiment he also proved that disease is blood-transmittable from animals ("Robert Koch...").

He continued to study anthrax and performed an experiment with pure bacilli to show that bacilli anthrax that had never made contact with animals can still cause anthrax by persisting as endospores under unsuitable conditions. Scientific workers continue to use the basis of these methods today ("Robert Koch...").

 Koch’s Postulates: ("What are Koch's...")

   1. The microorganism must be found in all organisms suffering from the disease, but not in healthy organisms

   2. The microorganism must be isolated from a diseased organism and grown in pure culture.

   3. The cultured microorganism should cause disease when introduced into a healthy organism.

   4. The microorganism must be reisolated from the inoculated, diseased experimental host and identified as being identical to the original specific causative agent.

 Other Contributions:

In 1893, Koch worked in Egypt and discovered vibro which causes cholera. He formed what is now the basic rules to controlling it ("Robert Koch..."). In 1896, Koch helped limit the outbreak of rinderpet in South Africa and helped to conrol TB by discovering that disease is more easily transmitted from men to men than from drinking water ("Robert Koch..."). In 1905, he proved that atoxyl is affective against human tryaphosomiases in Central Africa ("Robert Koch...")

Koch’s work on bacteriology is significant because he has saved many people’s lives from diseases such as typhoid, diphtheria, tetanus, syphilis, and anthrax by finding the organism responsible for them using his set of postulates which are still used today in etiology ("Robert Koch...").

 How does this affect me?

Thanks to Koch’s findings, I don’t have to worry about wondering how an infectious disease foments. Scientists today know exactly how to conduct their experiements when searching for what causes a disease. Without his findings, I probably would not be studying microbiology efficiently because he developed many modifications with lab procedures which are used today.

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    - Antony Leeuwenhoek

    - Robert Hooke

    - Edward Jenner

    - Louis Pasteur

    - Joseph Lister

    - Robert Koch

    - Walter Reed

    - Paul Ehrlich

    - Alexander Fleming

    - Kary Mullis